The integration of culture and tourism continues to improve museums’ popularity among tourists. Tourists’ needs for their tourism experience and the particularity of the museum as an indoor cultural leisure space has prompted museums to apply modern network technology to build a WeChat interpretation service system. This paper obtains data through a questionnaire survey, taking Nanjing Museum as an example. The study applies leisure restriction theory combined with the museum tourism environment and tourists’ behavioral characteristics and constructs a visitor use intention Model of the WeChat Interpretation System using the four dimensions of “attitude,” “behavior condition,” “interpersonal relationship,” and “structure.” We analyze the characteristics and restriction mechanism of tourists’ willingness to use the museum’s WeChat interpretation system. The results show that: (1) “attitude” and “interpersonal relationship” both have a positive impact on the tourists’ use intention, while “behavior condition” and “structure” have no significant effect on the use intention of the WeChat interpretation system; (2) The interaction of each dimension is as follows: “attitude” and “behavior condition” have a positive impact on “interpersonal relationship,” “attitude” positively affects “structure,” and “interpersonal relationship” and “behavior condition” have a positive impact on “structure.”